Bretécher was born in Nantes and got her first break as an illustrator when she was asked to provide the artwork for Le Facteur Rhésus by René Goscinny for L'Os à Moelle in 1963. She went on to work for several popular magazines and in 1969 invented the character "Cellulite". In 1972 she joined Gotlib and Mandryka in founding the Franco-Belgian comics magazine L'Écho des savanes.
Throughout the 1970s and 1980s, she published successful collections, such as The Destiny of Monique (1982). In 2001, Bretécher's series Agrippine was adapted into a 26-episode TV series by Canal+. (Wikipedia)
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